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- Title
Mortality and morbidity in extremely preterm infants (22 to 26 weeks of gestation): Austria 1999-2001.
- Authors
Weber, Christina; Weninger, Manfred; Klebermass, Katrin; Reiter, Gernot; Wiesinger-Eidenberger, Gabriele; Brandauer, Mathias; Kraschl, Raimund; Lingitz, Karl; Graßl-Jurek, Renate; Sterniste, Walter; Balluch, Bernd; Kolmer, Micha; Bruckner, Robert; Schweintzger, Gerolf; Salzer, Hans; Rath, Irene; Kubitsch, Peter; Zissler, Werner; Müller, Wilhelm; Urlesberger, Berndt
- Abstract
OBJECTIVE: The aim of this retrospective study was to analyze the mortality and morbidity for extremely preterm infants with a gestational age from 22 to 26 weeks. All infants were born in Austria during the years 1999-2001. METHODS: Data were collected from 16 neonatal intensive care units in Austria. Main outcome criteria were mortality, the rates of chronic lung disease (CLD) and severe retinopathy of prematurity (ROP, stage ≥3) to determine the short-term outcome; the rate of cerebral palsy (CP) at the corrected age of twelve months to assess the long-term outcome. RESULTS: Overall, 796 preterm infants with a gestational age less than 27 weeks were born in Austria and 581 (73%) were registered as live-born infants. Of those live born, 508 (87%) were analyzed. The mortality rates were 83%, 76%, 43%, 26% and 13% for 22, 23, 24, 25 and 26 weeks' gestation, respectively. The rates of CLD were 33% (22 weeks), 36% (23 weeks), 42% (24 weeks), 31% (25 weeks) and 22% (26 weeks). The rates of ROP of stage ≥3 were 0% (22 weeks), 29% (23 weeks), 23% (24 weeks), 18% (25 weeks) and 10% (26 weeks). The rates of CP at the corrected age of 12 months were 33%, 50%, 33%, 26% and 25% for 22, 23, 24, 25 and 26 weeks' gestation, respectively. CONCLUSIONS: The results of this national study are in accordance with the international literature: mortality and morbidity increased with decreasing gestational age.
- Publication
Wiener Klinische Wochenschrift, 2005, Vol 117, Issue 21/22, p740
- ISSN
0043-5325
- Publication type
Article
- DOI
10.1007/s00508-005-0468-y