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- Title
Accelerometer‐determined physical activity and cognitive function in middle‐aged and older adults from two generations of the Framingham Heart Study.
- Authors
Spartano, Nicole L.; Demissie, Serkalem; Himali, Jayandra J.; Dukes, Kimberly A.; Murabito, Joanne M.; Vasan, Ramachandran S.; Beiser, Alexa S.; Seshadri, Sudha
- Abstract
Introduction: Physical activity (PA) may play a role in maintenance of cognitive function in both middle and older ages and prevention of outcomes such as dementia and Alzheimer's disease. Methods: Cross‐sectional regression analyses were performed in Framingham Heart Study Third Generation (n = 1861) and Offspring (n = 909) cohort participants assessing the association of accelerometry‐measured PA with cognitive function, adjusting for age, sex, accelerometer wear time, education, occupational status/PA, and smoking status. Results: In each cohort, achieving just 10–21.4 min/day moderate‐to‐vigorous PA related to better executive function (P <.02); and just 10 min/day moderate‐to‐vigorous PA was associated with better verbal memory in middle‐aged adults in the Third Generation cohort (P =.02). In older adults of the Offspring cohort, total PA (measured in steps/day) was associated with better executive function (P <.02). Discussion: PA at levels lower than the current PA Guidelines (just 10 min/day moderate‐to‐vigorous PA and total PA including lower intensity PA) were associated with better cognitive function. Highlights: •Physical activity related to better cognition in middle‐aged and older adults.•Just 10 minutes of moderate‐to‐vigorous activity related to better cognition.•Walking more total steps/day is related to better executive function in older adults.
- Publication
Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2019, Vol 5, Issue 1, p618
- ISSN
2352-8737
- Publication type
Article
- DOI
10.1016/j.trci.2019.08.007