We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
甲基强的松龙治疗2型糖尿病合并突发性感音神经聋的临床疗效研究.
- Authors
朱筱; 李艳波; 刘国磊; 刘德情; 肖平; 秦佳俊; 李萍; 陈波
- Abstract
To observe the therapeutic effect of methylprednisolone in treatment of type 2 diabetes mellitus complicated with sudden sensorineural hearing loss. A total of 60 adult type 2 diabetic patients with unilateral sudden acoustic deafness who were hospitalized in the Department of Endocrine and Otorhinolaryngology of South China Hospital Affiliated to Shenzhen University from January 2018 to October 2020 were enrolled in this study. According to random number table method, they were divided into treatment group (n=30) and control group (n=30). Patients in both groups were treated with neurotrophic therapy, insulin hypoglycemic therapy and hyperbaric oxygen therapy. After 3 days of intravenous infusion of methylprednisolone, the dose of methylprednisolone was reduced and continued treatment for 4 days. The total course of treatment in both groups was 14 days. The improvement of hearing impairment after treatment was observed, Pure tone average (PTA) and auditory brainstem response (ABR) of two wo groups of patients were measured before treatment, 1 week after treatment and 2 weeks after treatment, respectively, to evaluate the treatment effect. 2 weeks after treatment, the grade of hearing impairment in the treatment group was better than that in the control group (P<0.05). 2 weeks after treatment, PTA and ABR indexes stimulated by 70dB, 80dB and 90dB sound waves in the treatment group were better than those in the control group (P<0.05). Combined therapy with methylprednisolone and nutritional nerve, hypoglycemic and hyperbaric oxygen can effectively improve the hearing of patients with type 2 diabetes mellitus complicated with sudden sensorineural hearing loss, and is worthy of clinical application.
- Subjects
SENSORINEURAL hearing loss; HYPERBARIC oxygenation; TYPE 2 diabetes; SOUND waves; INTRAVENOUS therapy
- Publication
Progress in Modern Biomedicine, 2022, Vol 22, Issue 1, p78
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2022.01.013