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- Title
Research progress on circadian clock genes in common abdominal malignant tumors (Review).
- Authors
SHENG-LI YANG; QUAN-GUANG REN; LU WEN; JIAN-LI HU; HENG-YI WANG
- Abstract
The circadian clock refers to the inherent biological rhythm of an organism, which, is accurately regulated by numerous clock genes. Studies in recent years have reported that the abnormal expression of clock genes is ubiquitous in common abdominal malignant tumors, including liver, colorectal, gastric and pancreatic cancer. In addition, the abnormal expression of certain clock genes is closely associated with clinical tumor parameters or patient prognosis. Studies in clock genes may expand the knowledge about the mechanism of occurrence and development of tumors, and may provide a new approach for tumor therapy. The present study summarizes the research progress in this field.
- Subjects
CIRCADIAN rhythms; ABDOMINAL tumors; BIOLOGICAL rhythms; GENE expression; ABDOMINAL surgery
- Publication
Oncology Letters, 2017, Vol 14, Issue 5, p5091
- ISSN
1792-1074
- Publication type
Article
- DOI
10.3892/ol.2017.6856