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- Title
Controlling elements in the mouse X-chromosome.
- Authors
Cattanach, B. M.; Perez, J. N.; Pollard, C. E.
- Abstract
The frequency and nature of the changes in ‘state’ of the mouse X-chromosome controlling element (inactivation centre) have been investigated on an inbred background. The results indicate with near-certainty that meiotic crossing over is the responsible mechanism and that the frequency of recombination between the T(1; X)Ct breakpoint and the locus of the controlling element is approximately 3%. Maize-type ‘changes in state’ may occur under other experimental conditions. The data do not distinguish on which side of the autosomal insertion the element lies but when combined with observations of other investigators suggest that the location must be on the Mo-Ta side and very close to Ta.
- Publication
Genetics Research, 1970, Vol 15, Issue 2, p183
- ISSN
0016-6723
- Publication type
Article
- DOI
10.1017/S0016672300001518