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- Title
Unusual contact allergens from plants in the family Hydrophyllaceae.
- Authors
Reynolds, Gary W.; Epstein, William L.; Rodriguez, Eloy
- Abstract
The dermatitic constituents of the glandular hairs of plants in the family Hydrophyllaceae comprise a class of uncommon natural products called "phacelioids". The chemical structures consist of various elaborations of hydroquinone attached to a C[subm] to C[subw] prenyl chain. Certain of these compounds are equivalent to the urushiols of Toxicodendron (Rhus) their capacity to sensitize humans Although structurally related to the urushiols, the phacelioids do not appear to cross-react in humans either with urushiol, or between phacelioids with different phenyl chains.
- Subjects
CONTACT dermatitis; HYDROPHYLLACEAE; PHACELIA; WIGANDIA; PHENOLS; URUSHIOL; TOXICODENDRON
- Publication
Contact Dermatitis (01051873), 1986, Vol 14, Issue 1, p39
- ISSN
0105-1873
- Publication type
Article
- DOI
10.1111/j.1600-0536.1986.tb01150.x