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- Title
Paraneoplastic Severe Sensorimotor Axonal Polyneuropathy in Pancreatic Neuroendocrine Carcinoma: A Case Report and Review of the Literature.
- Authors
Akbas, Turkay; Coskun, Sinem Kantarcioglu; Torun, Serkan; Ozturk, Ayhan; Esbah, Onur; Onbas, Omer
- Abstract
Objective: Paraneoplastic neurological syndromes (PNSs) are a diverse group of neurological disorders affecting any part of the nervous system before or during cancer. Case: A 78-year-old man first experienced pain and burning in the upper extremity three years previously, to which muscle weakness was added a short time later. The same symptoms developed in the lower extremities one year previously. He was admitted to the intensive care unit due to pneumonia and was conscious but quadriplegic with a modified Rankin score of 5. Abdominal computed tomography showed mass lesions in the liver and pancreas. Biopsies revealed pancreatic small cell neuroendocrine carcinoma. Electrophysiological studies revealed severe sensorimotor axonal polyneuropathy. Paraneoplastic sensorimotor axonal polyneuropathy was diagnosed since other causes of polyneuropathy had been excluded. Palliative care was considered due to the patient's poor functional state. Conclusions: Early diagnosis of cancer is of paramount importance in patients with PNSs if appropriate treatment is to be provided.
- Subjects
DIAGNOSIS of neurological disorders; PANCREATIC tumors; PARANEOPLASTIC syndromes; BIOPSY; ELECTROPHYSIOLOGY; NEUROENDOCRINE tumors; COMPUTED tomography; QUADRIPLEGIA; ABDOMINAL radiography
- Publication
Konuralp Medical Journal / Konuralp Tip Dergisi, 2022, Vol 14, Issue 2, p424
- ISSN
1309-3878
- Publication type
Article
- DOI
10.18521/ktd.1019045