We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Metastasis to the oral and maxillofacial region: A systematic review.
- Authors
Kirschnick, Laura Borges; Schuch, Lauren Frenzel; Cademartori, Mariana Gonzalez; Vasconcelos, Ana Carolina Uchoa
- Abstract
Objectives: The purpose of this systematic review was to incorporate the information published on metastatic lesions in the in the oral and maxillofacial region into a comprehensive analysis of their demographic, clinical, and imaginological features and survival rate. Materials and methods: An electronic search was undertaken in the subsequent databases: PubMed, Web of Science, Scopus, EMBASE, and LILACS. All papers included were case reports or case series. Absolute and relative frequencies were obtained by descriptive analysis. Overall survival was defined by the Kaplan–Meier method. Results: This systematic review identified 217 studies from 33 countries, comprising 348 cases. Male individuals were more affected (n = 199/57.68%) in the 5th to 7th decades of life. The most usual primary site was the lung in men (n = 49/14.08%) and the breast in women (n = 40/11.49%). Jawbones were affected in 183 cases (53.19%), with the posterior mandible (n = 96/66.66%) representing the preferred site. In soft tissues, the gingiva (n = 80/23.25%) was more affected. Clinical presentation was a nodular mass with or without ulceration (n = 280/85.89%). Imaginological examinations revealed radiolucent/hypodense lesions (n = 115/59.28%). The mean survival time was eight months. Conclusion: Despite the rare occurrence of metastatic lesions in the oral and maxillofacial region, the current systematic review offers substantial data that could assist clinicians and surgeons.
- Subjects
HEAD tumors; ONLINE information services; GINGIVAL neoplasms; MOUTH tumors; MEDICAL information storage &; retrieval systems; JAW tumors; SYSTEMATIC reviews; METASTASIS; LUNG tumors; KAPLAN-Meier estimator; SURVIVAL analysis (Biometry); DESCRIPTIVE statistics; MEDLINE; NECK tumors; BREAST tumors; SYMPTOMS
- Publication
Oral Diseases, 2022, Vol 28, Issue 1, p23
- ISSN
1354-523X
- Publication type
Article
- DOI
10.1111/odi.13611