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- Title
Sex Differences in Cognitive Changes in De Novo Parkinson's Disease.
- Authors
Bayram, Ece; Banks, Sarah J.; Shan, Guogen; Kaplan, Nikki; Caldwell, Jessica Z.K.
- Abstract
Objective: To evaluate the sex differences in cognitive course over 4 years in Parkinson's disease (PD) patients with and without mild cognitive impairment (MCI) compared to controls. Methods: Four-year longitudinal cognitive scores of 257 cognitively intact PD, 167 PD-MCI, and 140 controls from the Parkinson's Progression Markers Initiative were included. Longitudinal scores of men and women, and PD with and without MCI were compared. Results: Women had better verbal memory, men had better visuospatial function. There was no interaction between sex, diagnostic group, and/or time (4-year follow-up period). Conclusions: Sex differences in cognitive course in de novo PD are similar to healthy aging. Cognitive decline rates in PD with and without MCI are similar for the first 4 years of PD.
- Subjects
PARKINSON'S disease; VERBAL memory; HUMAN sexuality
- Publication
Journal of the International Neuropsychological Society, 2020, Vol 26, Issue 2, p241
- ISSN
1355-6177
- Publication type
Article
- DOI
10.1017/S1355617719001085