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- Title
The potential roles of circRNAs in osteoarthritis: a coming journey to find a treasure.
- Authors
Hui-Zi Li; Zhong Lin; Xiang-He Xu; Nan Lin; Hua-Ding Lu
- Abstract
Osteoarthritis (OA), a common joint disease in elderly, causes serious social and economic burdens worldwide. Previous studies indicated that some differentially expressed circular RNAs (circRNAs) participated in the initiation and progression of OA. These findings suggested that circRNAs may act as promising diagnostic biomarkers and therapeutic targets for OA. In this review, we summarize the biogenesis and biological functions of circRNAs and explore the underlying roles of circRNAs in OA, which may enlighten further studies and contribute to the early diagnosis and intervention of OA.
- Publication
Bioscience Reports, 2018, Vol 38, Issue 5, p1
- ISSN
0144-8463
- Publication type
Article
- DOI
10.1042/BSR20180542