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- Title
Carbonate apatite versus ß-tricalcium phosphate for rat vertical bone augmentation: A comparison of bioresorbable bone substitutes using polytetrafluoroethylene tubes.
- Authors
Makiko YANO; Kenichirou YASUI; Jun-ichiro JO; Aki NISHIURA; Yoshiya HASHIMOTO; Naoyuki MATSUMOTO
- Abstract
This study radiologically and histologically compared two bioresorbable bone substitutes with different compositions carbonate apatite (Cytrans® Granules; CGs) and ß-tricalcium phosphate (ß-TCP) for vertical bone augmentation on a rat skull using a polytetrafluoroethylene (PTFE) tubes. This PTFE tube was placed at the center of the skull, fixed with Super Bond, and augmented with CGs or ß-TCP granules. Specimens with surrounding tissue were harvested at 4, 8, and 12 weeks postoperatively, and radiological and histological evaluations were performed. The bone volume to total volume ratio (BV/TV) of the ß-TCP-implanted group was markedly higher than that of the CG-implanted group at 4 and 12 weeks postoperatively. Compared to CGs, ß-TCP exhibited the ability to form blood vessels into the graft material for a short period after transplantation, as well as an elevated production of collagen into ß-TCP granules during the bone formation process.
- Subjects
BONE substitutes; BONE grafting; APATITE; POLYTEF; PHOSPHATES
- Publication
Dental Materials Journal, 2023, Vol 42, Issue 6, p851
- ISSN
0287-4547
- Publication type
Article
- DOI
10.4012/dmj.2023-112