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- Title
The Longitudinal High-Pressure Zone Profile in Patients With Fecal Incontinence.
- Authors
Österberg, A.; Graf, W.; Påhlman, L.
- Abstract
OBJECTIVE: The aim of this study was to evaluate differences in the longitudinal high-pressure zone (HPZ) profile between incontinent patients and healthy controls. METHODS: One hundred and fifty-six patients with fecal incontinence (mean age 63 yr; 139 women, 17 men) and 25 healthy controls (mean age 54 yr; 20 women, five men) underwent anorectal manometry with a perfused catheter using a station pull-through technique. RESULTS: Maximum resting pressure (MRP) and maximum squeeze pressure (MSP) were lower in patients (<em>p</em> < 0.001) and the HPZ was shorter in patients (<em>p</em> < 0.05). The ratio MRP/sum of resting pressures within HPZ did not differ between the groups. The severity of incontinence measured as an incontinence score was correlated to MSP (<em>p</em> < 0.05) and sum of squeeze pressure within HPZ (<em>p</em> < 0.05), but not to any other variable. The relative pressure amount during rest in the distal half of HPZ was higher in controls (63% vs 56%, <em>p</em>< 0.05). but this was not seen during squeeze. CONCLUSIONS: These results suggest that the main difference between incontinent patients and healthy controls is a greater magnitude of the pressure profile in the latter group. Furthermore, the relative pressure accumulation during rest tended to be more distally located within the HPZ.
- Subjects
FECAL incontinence; DEFECATION disorders; CONSTIPATION; GASTROINTESTINAL diseases; HIGH pressure biochemistry
- Publication
American Journal of Gastroenterology (Springer Nature), 1999, Vol 94, Issue 10, p2966
- ISSN
0002-9270
- Publication type
Article
- DOI
10.1111/j.1572-0241.1999.01373.x