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- Title
Genital Kaposi sarcoma in a HIV and syphilis co-infected patient: case presentation.
- Authors
Barroso dos Reis, Helena Lucia; de Carvalho Ferreira, Dennis; Tosato Boldrini, Neide Aparecida; Galvão, Carolina; Jacomele Caldas, João Victor; Santos Neves, Marize Freitas; Godefroy, Philippe
- Abstract
<bold>Background: </bold>Kaposi sarcoma, as an epidemiological factor, is associated with acquired immunodeficiency syndrome (AIDS) and it is related to human herpes virus (HHV-8), as well as a higher prevalence in males and non-genital involvement. Vulvar localization is quite infrequent; therefore it may be considered in the differential diagnosis of genital lesions, especially in HIV patients.<bold>Case Presentation: </bold>We describe the atypical presentation of a female HIV patient with multiple comorbidities, with the clinical manifestation of Kaposi sarcoma (KS) in a vulvar region that was initially diagnosed as a syphilitic gumma. The patient underwent a biopsy of the lesion, and histopathology revealed a Kaposi sarcoma.<bold>Discussion: </bold>This case reinforces that the pathogenesis of Kaposi sarcoma is still unclear and that probably multiple factors, regarding both the virus and the patient characteristics may lead to carcinogenesis.<bold>Conclusion: </bold>It is imperative to seek more excellent knowledge about this disease, to facilitate the diagnosis, to warrant the appropriate treatment and to improve the prognosis of the patient, especially the genital lesions.
- Subjects
KAPOSI'S sarcoma; AIDS; PATHOLOGY; VULVAR cancer; HIV-positive persons; HIV; SYPHILIS
- Publication
BMC Infectious Diseases, 2019, Vol 19, Issue 1, p1
- ISSN
1471-2334
- Publication type
journal article
- DOI
10.1186/s12879-019-4714-8