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- Title
Comparison Between 30:1 and 30:2 Compression-to-ventilation Ratios for Cardiopulmonary Resuscitation: Are Two Ventilations Necessary?
- Authors
Cha, Kyoung ‐ Chul; Kim, Yong Won; Kim, Tae Hoon; Jung, Woo Jin; Yook, Hyun; Choi, Eunhee; Cha, Yong Sung; Kim, Oh Hyun; Kim, Hyun; Lee, Kang Hyun; Hwang, Sung Oh; Olson, James E.
- Abstract
Objectives Controversy is continuing over the need for ventilation and the optimal compression-ventilation ( CV) ratio during cardiopulmonary resuscitation ( CPR). The aim of this study was to comparatively elucidate the effect on hemodynamics and arterial oxygen saturation of a single ventilation relative to two consecutive ventilations during CPR in a dog model of cardiac arrest. Methods Twenty mongrel dogs were divided into two groups. After 3 minutes of ventricular fibrillation ( VF), the single-ventilation group received CPR with a 30:1 CV ratio, and the two-ventilation group received CPR with a 30:2 CV ratio, all with room air for 7 minutes. Thereafter, continuous chest compressions and intermittent ventilation at rate of 10 per minute were followed for both groups for 10 minutes. Hemodynamic parameters, arterial blood gas profiles, and variables from CPR were compared at baseline and at 5, 10, 15, and 20 minutes after induction of VF. Results Hemodynamic parameters including aortic systolic and diastolic pressures, right atrial systolic and diastolic pressures, coronary perfusion pressure, end-tidal carbon dioxide tension, and arterial blood gas profiles including arterial oxygen tension, arterial oxygen saturation, and arterial carbon dioxide tension were not different between two groups during CPR. In the 30:1 group, the period of compression interruption was shorter and chest compression fraction was higher than that in the 30:2 group (6 sec/min vs. 10.9 sec/min, p < 0.001; 90.0% vs. 81.8%, p < 0.001). Conclusions CPR with a 30:1 CV ratio, compared to CPR with a 30:2 CV ratio, results in comparable arterial oxygenation saturation and hemodynamics.
- Subjects
CORONARY artery physiology; ARTERIAL physiology; CARDIOPULMONARY resuscitation; ACTIVE oxygen in the body; ANIMAL experimentation; BLOOD gases analysis; BLOOD pressure; BLOOD pressure measurement; BODY weight; DOGS; EMERGENCY medicine; HEMODYNAMICS; MEDICAL care; MEDICAL protocols; PATIENTS; PERFUSION; SURVIVAL; VENTILATION; COMPRESSION therapy; DATA analysis software; DESCRIPTIVE statistics
- Publication
Academic Emergency Medicine, 2015, Vol 22, Issue 11, p1261
- ISSN
1069-6563
- Publication type
Article
- DOI
10.1111/acem.12796