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- Title
Experiencia del tratamiento de hipertensión arterial pulmonar persistente en un centro hospitalario.
- Authors
Antonio González-López, Ramón; Iglesias-Leboreiro, José; Bernárdez-Zapata, Isabel; Enrique Rendón-Macías, Mario
- Abstract
Introduction: Persistent pulmonary hypertension (PPH) of the newborn is a common condition in neonatal therapies, especially when products are premature. Objective: To describe the therapeutic schemes used in PPH by gestational age groups. Material and methods: The treatments received by weeks of gestational age (WGA) groups (24-31, 32-34, 35-37 and 38-40 WGA) were reviewed. Results: We studied 98 neonates. In 12 (12.2%) treatment was only with ventilation and metabolic support, the rest required at least one antihypertensive drug. The most commonly drugs used were: nitric oxide, sildenafil and milrinone. 39 (39.8%) required a combination. 53.1% (n = 51) were discharged with normal or mild hypertension pulmonary arterial pressure. There were 6 (6.1%) deaths. Patients with < 32 WGA required more drugs to control pulmonary hypertension. Conclusion: Control of PPH is based on improving oxygenation and lung recruitment. Given the diversity of pharmacological treatments conducting multicenter clinical trials and developing clinical guidelines are needed.
- Publication
Revista Mexicana de Pediatria, 2017, Vol 84, Issue 2, p48
- ISSN
0035-0052
- Publication type
Article