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Antimalarial and antitumour activities of the steroidal quinone-methide celastrol and its combinations with artemiside, artemisone and methylene blue.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.988748
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Anti-Melanoma Activities of Artemisone and Prenylated Amino-Artemisinins in Combination With Known Anticancer Drugs.
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- Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.558894
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- Article
Titelbild: Artemisone—A Highly Active Antimalarial Drug of the Artemisinin Class (Angew. Chem. 13/2006).
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- Angewandte Chemie, 2006, v. 118, n. 13, p. 2041, doi. 10.1002/ange.200690045
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Artemisone—A Highly Active Antimalarial Drug of the Artemisinin ClassWork at the HKUST was funded by Bayer AG Central Research, Leverkusen, the Institute of Molecular Technology for Drug Discovery and Synthesis through the HKSAR University Grants Committee Areas of Excellence Fund, and the HKSAR Research Grants Council through the Competitive Earmarked Research Grants Scheme. The Medicines for Malaria Venture (MMV), Geneva, also provided financial support of the work at Bayer, and through Bayer at HKUST and other centers. Dr. W. Collins (Centers for Disease Control, Atlanta) supplied P. falciparum FVO strain used for the primate studies.
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- Angewandte Chemie, 2006, v. 118, n. 13, p. 2136, doi. 10.1002/ange.200503071
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Efficacies and ADME properties of redox active methylene blue and phenoxazine analogues for use in new antimalarial triple drug combinations with amino-artemisinins.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2023.1308400
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Cover Picture: Artemisone—A Highly Active Antimalarial Drug of the Artemisinin Class (Angew. Chem. Int. Ed. 13/2006).
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- Angewandte Chemie International Edition, 2006, v. 45, n. 13, p. 1989, doi. 10.1002/anie.200690045
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- Article
Artemisone—A Highly Active Antimalarial Drug of the Artemisinin ClassWork at the HKUST was funded by Bayer AG Central Research, Leverkusen, the Institute of Molecular Technology for Drug Discovery and Synthesis through the HKSAR University Grants Committee Areas of Excellence Fund, and the HKSAR Research Grants Council through the Competitive Earmarked Research Grants Scheme. The Medicines for Malaria Venture (MMV), Geneva, also provided financial support of the work at Bayer, and through Bayer at HKUST and other centers. Dr. W. Collins (Centers for Disease Control, Atlanta) supplied P. falciparum FVO strain used for the primate studies.
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- Angewandte Chemie International Edition, 2006, v. 45, n. 13, p. 2082, doi. 10.1002/anie.200503071
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- Article
Facile Preparation of N-Glycosylated 10-Piperazinyl Artemisinin Derivatives and Evaluation of Their Antimalarial and Cytotoxic Activities.
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- Molecules, 2018, v. 23, n. 7, p. 1713, doi. 10.3390/molecules23071713
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- Article
The evaluation of the anti‐cancer drug elesclomol that forms a redox‐active copper chelate as a potential anti‐tubercular drug.
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- IUBMB Life, 2019, v. 71, n. 5, p. 532, doi. 10.1002/iub.2002
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Preliminary Evaluation of Artemisinin–Cholesterol Conjugates as Potential Drugs for the Treatment of Intractable Forms of Malaria and Tuberculosis.
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- ChemMedChem, 2018, v. 13, n. 1, p. 67, doi. 10.1002/cmdc.201700579
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Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Asexual and Transmissible Malaria Parasites.
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- ChemMedChem, 2017, v. 12, n. 24, p. 2086, doi. 10.1002/cmdc.201700599
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Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Neospora caninum and Comparative Cytotoxicities.
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- ChemMedChem, 2017, v. 12, n. 24, p. 2094, doi. 10.1002/cmdc.201700600
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Methylene Homologues of Artemisone: An Unexpected Structure–Activity Relationship and a Possible Implication for the Design of C10-Substituted Artemisinins.
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- ChemMedChem, 2016, v. 11, n. 13, p. 1469, doi. 10.1002/cmdc.201600011
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Interactions between Artemisinins and other Antimalarial Drugs in Relation to the Cofactor Model-A Unifying Proposal for Drug Action.
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- ChemMedChem, 2012, v. 7, n. 12, p. 2204, doi. 10.1002/cmdc.201200383
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A Partial Convergence in Action of Methylene Blue and Artemisinins: Antagonism with Chloroquine, a Reversal with Verapamil, and an Insight into the Antimalarial Activity of Chloroquine.
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- ChemMedChem, 2011, v. 6, n. 9, p. 1603, doi. 10.1002/cmdc.201100184
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Preparation of N-Sulfonyl- and N-Carbonyl-11-Azaartemisinins with Greatly Enhanced Thermal Stabilities: in vitro Antimalarial Activities.
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- ChemMedChem, 2007, v. 2, n. 10, p. 1464, doi. 10.1002/cmdc.200700065
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Artesunate and Dihydroartemisinin (DHA): Unusual Decomposition Products Formed under Mild Conditions and Comments on the Fitness of DHA as an Antimalarial Drug.
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- ChemMedChem, 2007, v. 2, n. 10, p. 1448, doi. 10.1002/cmdc.200700064
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Repurposing of antiparasitic drugs: the hydroxy-naphthoquinone buparvaquone inhibits vertical transmission in the pregnant neosporosis mouse model.
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- Veterinary Research, 2016, v. 47, p. 1, doi. 10.1186/s13567-016-0317-1
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- Article