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- Title
Combined classical spindle cell/pleomorphic lipoma spectrum imaging and clinical data.
- Authors
Younan, Yara; Martinez, Anthony; Reimer, Nickolas; Edgar, Mark; Gonzalez, Felix; Umpierrez, Monica; Subhawong, Ty; Singer, Adam D.
- Abstract
<bold>Objectives: </bold>Compile the largest study to date on the imaging and clinical features of the classic spindle cell/pleomorphic lipoma spectrum and suggest this diagnosis be included in the differential for benign and malignant macroscopic fat-containing soft tissue masses regardless of the mass location or patient demographics.<bold>Materials and Methods: </bold>An institutional search was performed to identify all available classic-type spindle cell/pleomorphic lipomas with available demographic and imaging data. Images and reports were analyzed by one MSK-trained radiologist and radiographic, anatomic and clinical data were recorded. Additionally, a literature search was performed to identify studies describing the spindle cell lipoma spectrum imaging features and were combined with institutional data.<bold>Results: </bold>Forty-two institutional cases were identified, 37 of which had MRIs performed among which 21 had images available (T1- and T2-weighted pulse sequences) for review while the remainder had outside reports detailing the mass imaging features. There was a mean age of 57 with 79% of cases occurring in males. Contrary to prior reports, 57% of masses were subcutaneous, and the neck and back region accounted for 26% of cases. When the institutional cases were combined with available data in the literature, there was a new sample size of 91 masses, 74 of which had MRI and/or CT data. Eighty-seven percent of masses were heterogeneous, 51% were composed of less than 75% fat, 65% were in the back, neck or shoulder region, 27% of masses were deep and 91% demonstrated enhancement. Eighty-two percent of patients were males with a mean age of 58 at excision.<bold>Conclusion: </bold>Imaging features, patient demographics and tumor location alone are not enough to differentiate tumors of the spindle cell lipoma spectrum from other macroscopic fat-containing benign and malignant tumors, and these entities should be included in the same imaging differential diagnosis.
- Subjects
LIPOMA; SARCOMA; SOFT tissue tumors; MEDICAL radiography; SPECTRUM analysis; DIAGNOSIS; DIFFERENTIAL diagnosis; RETROSPECTIVE studies; SURGERY
- Publication
Skeletal Radiology, 2018, Vol 47, Issue 1, p51
- ISSN
0364-2348
- Publication type
journal article
- DOI
10.1007/s00256-017-2751-1