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- Title
Towards risk stratification in systemic atherosclerosis: value of myocardial function and viability imaging as an adjunct to MR angiography.
- Authors
Seeger A; Fenchel M; Kramer U; Bretschneider C; Grimm F; Klumpp B; Scheule A; Balletshofer B; Claussen CD; Miller S; Seeger, Achim; Fenchel, Michael; Kramer, Ulrich; Bretschneider, Christiane; Grimm, Florian; Klumpp, Bernhard; Scheule, Albertus; Balletshofer, Bernd; Claussen, Claus D; Miller, Stephan
- Abstract
<bold>Objectives: </bold>To longitudinally assess the value of cardiac functional and viability imaging as a supplement to MR angiography in patients with atherosclerotic disease.<bold>Methods: </bold>Cardiac MRI was performed in 195 consecutive patients with symptomatic peripheral arterial disease. Of these, 186 patients were followed for 22 +/- 5 months for the presence of cardiac events (cardiac death, acute coronary syndrome and hospitalisation as a result of congestive heart failure).<bold>Results: </bold>Myocardial viability imaging showed a high prevalence of known (n = 31) and occult myocardial infarctions (MI) (n = 26). Cardiac events occurred more often in patients with reduced ventricular function (ejection fraction (EF) less than 40%, cardiac event in 4/8 patients; EF 40-55%, cardiac event in 10/40 patients; EF greater than 55%, cardiac event in 15/138 patients) as well as in patients with occult MI (8/25 patients) and known MI (11/30 patients). In patients with normal function, the detection of a previous MI was of high relevance to prognosis.<bold>Conclusions: </bold>Both reduced EF and the presence of MI influence patients' prognoses. Performing cardiac MRI in this patient population may influence further patient management including intensified risk factor intervention.
- Publication
European Radiology, 2010, Vol 20, Issue 4, p838
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-009-1607-z