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- Title
A novel retractable laparoscopic device for mapping gastrointestinal slow wave propagation patterns.
- Authors
O'Grady, Gregory; Cheng, Leo; Berry, Rachel; Paskaranandavadivel, Niranchan; Du, Peng; Trew, Mark; Windsor, John; Trew, Mark L; Windsor, John A; Cheng, Leo K
- Abstract
<bold>Background: </bold>Gastric slow waves regulate peristalsis, and gastric dysrhythmias have been implicated in functional motility disorders. To accurately define slow wave patterns, it is currently necessary to collect high-resolution serosal recordings during open surgery. We therefore developed a novel gastric slow wave mapping device for use during laparoscopic procedures.<bold>Methods: </bold>The device consists of a retractable catheter constructed of a flexible nitinol core coated with Pebax. Once deployed through a 5-mm laparoscopic port, the spiral head is revealed with 32 electrodes at 5 mm intervals. Recordings were validated against a reference electrode array in pigs and tested in a human patient.<bold>Results: </bold>Recordings from the device and a reference array in pigs were identical in frequency (2.6 cycles per minute; p = 0.91), and activation patterns and velocities were consistent (8.9 ± 0.2 vs 8.7 ± 0.1 mm s-1; p = 0.2). Device and reference amplitudes were comparable (1.3 ± 0.1 vs 1.4 ± 0.1 mV; p = 0.4), though the device signal-to-noise ratio was higher (17.5 ± 0.6 vs 12.8 ± 0.6 dB; P < 0.0001). In the human patient, corpus slow waves were recorded and mapped (frequency 2.7 ± 0.03 cycles per minute, amplitude 0.8 ± 0.4 mV, velocity 2.3 ± 0.9 mm s-1).<bold>Conclusion: </bold>In conclusion, the novel laparoscopic device achieves high-quality serosal slow wave recordings. It can be used for laparoscopic diagnostic studies to document slow wave patterns in patients with gastric motility disorders.
- Subjects
GASTRIC diseases; ARRHYTHMIA; NICKEL-titanium alloys; LAPAROSCOPIC surgery; GASTROINTESTINAL diseases; PHYSIOLOGY; EQUIPMENT &; supplies; STOMACH physiology; LAPAROSCOPY; ANIMAL experimentation; ELECTRODES; ELECTROPHYSIOLOGY; GASTROINTESTINAL motility; MICROSURGERY; RESEARCH funding; SIGNAL processing; SWINE
- Publication
Surgical Endoscopy & Other Interventional Techniques, 2017, Vol 31, Issue 1, p477
- ISSN
1866-6817
- Publication type
journal article
- DOI
10.1007/s00464-016-4936-4