We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Influence of matrix on the bioavailability of nine fungicides in wine grape and red wine.
- Authors
Oliva, J.; Martínez, G.; Cermeño, S.; Motas, M.; Barba, A.; Cámara, M. A.
- Abstract
The influence of the matrix and the concentration of the pesticides on the bioavailability of the dimethomorph, ametoctradin, boscalid, fenhexamid, mepanipyrim, cyazofamid, kresoxim-methyl, pyraclostrobin, and metrofenone fungicides in grapes and red wine are studied. Bioavailability is calculated using an in vitro procedure and by simulating human gastric digestion by dialyzation of the fungicides at six concentrations (0.1, 0.5, 1, 2, 5, and 10 mg kg−1) in the semipermeable cellulose membrane. Analyses were carried out by QuEChERS extraction method and liquid chromatography with mass spectrometry with a triple quadrupole analyzer detection (LC-MS/MS QqQ). The results indicated a clear effect of the concentration and matrix, with dialyzation in grapes and red wine beginning in some fungicides from just 2 mg kg1, and in water from 5 mg kg−1. The different matrices can also be ordered according to the matrix effect: water > red wine > grape. The fungicides which present greatest bioavailability are, in order: ametoctradin in grape and red wine, boscalid in red wine and water, dimethomorph in water, and fenhexamid in red wine and water.
- Subjects
FUNGICIDE analysis; RED wines; GRAPE microbiology; LIQUID chromatography; EXTRACTION techniques
- Publication
European Food Research & Technology, 2018, Vol 244, Issue 6, p1083
- ISSN
1438-2377
- Publication type
Article
- DOI
10.1007/s00217-017-3031-y