We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The case of a 30‐year‐old man with subacute gait instability, weakness, and muscle spasms.
- Authors
Mehta, Mitesh P.; Sokol, Leonard L.
- Abstract
Case Summary: A 30‐year‐old healthy man presents after a fall with diffuse weakness and pain and recent onset left eye ptosis in the setting of three weeks of progressive bilateral leg weakness, gait instability, and difficulty washing his hair due to upper extremity weakness. He had also developed stiffness in his neck and shoulders and uncontrollable muscle spasms. Exam was notable for ptosis, fatiguing weakness in extremities, increased tone, hyperreflexia with clonus, and spastic gait. A mediastinal mass was found on chest CT (Fig. 1), and biopsy confirmed an invasive thymoma with positive nodes. Serum testing was positive for antibodies to acetylcholine receptors as well as glutamic acid decarboxylase.
- Subjects
SPASMS; GLUTAMATE decarboxylase; MYASTHENIA gravis; BLEPHAROPTOSIS; HAIR washing; CHOLINERGIC receptors; RECEPTOR antibodies
- Publication
Annals of Clinical & Translational Neurology, 2020, Vol 7, Issue 12, p2535
- ISSN
2328-9503
- Publication type
Article
- DOI
10.1002/acn3.51181