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- Title
Psychological factors associated with failure of detoxification treatment in chronic headache associated with medication overuse.
- Authors
Bottiroli, S.; Viana, M.; Sances, G.; Ghiotto, N.; Guaschino, E.; Pazzi, S.; Nappi, G.; Tassorelli, C.; Galli, F.; Vegni, E.
- Abstract
Aim: The aim of this study was to evaluate the psychological factors associated with a negative outcome following detoxification in a 2-month follow-up in medication-overuse headache. Methods: All consecutive patients entering the detoxification program were analysed in a prospective, non-randomised fashion. Psychiatric conditions and personality characteristics were assessed using the Structured Clinical Interview for DSM-IV Disorders (SCID-I) and the Minnesota Multiphasic Personality Inventory (MMPI)-2. χ2 tests, one-way analyses of variance, and odds ratios (ORs) were used. Results: A total of 248 patients completed the follow-up: 156 stopped overuse and their headaches reverted to an episodic pattern (Group A); 23 kept overusing without any benefit on headache frequency (Group B); and 51 stopped overuse without any benefit on headache frequency (Group C). The prognostic factors for the outcome of Group B were higher scores on the correction (OR 1.128; p = 0.036), depression (OR 1.071; p = 0.05), hysteria (OR 1.106; p = 0.023), and overcontrolled hostility (OR 1.182; p = 0.04) MMPI-2 scales, whereas those for Group C were psychiatric comorbidities (OR 1.502; p = 0.021) and higher scores on the hysteria scale (OR 1.125; p = 0.004). Conclusions: The outcome of detoxification is influenced by psychological factors that should be considered when considering treatment strategies.
- Subjects
DETOXIFICATION (Substance abuse treatment); FAILURE (Psychology); HEADACHE; PERSONALITY; SUBSTANCE abuse treatment; HEALTH outcome assessment; PSYCHOLOGY; PATIENTS
- Publication
Cephalalgia, 2016, Vol 36, Issue 14, p1356
- ISSN
0333-1024
- Publication type
Article
- DOI
10.1177/0333102416631960