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- Title
Retrospective Analysis and Summary on Efficacy of Jianpi Shengxue Tablet in the Treatment of Iron Deficiency Anemia.
- Authors
Jinqing LI; Longjiao CONG; Muchen LI; Chongluan SHI; Wenlan LIU; Wenjuan WANG; Naidong HU
- Abstract
[Objectives] The research aimed to make a retrospective analysis and summary on the efficacy of Jianpi Shengxue Tablet in the treatment of iron deficiency anemia. [Methods] A total of 200 patients with iron deficiency anemia who were treated at outpatient in Tongzhou District of Dongzhimen Hospital of Beijing University of Chinese Medicine from January 1, 2017 to October 30, 2020 were selected as the research objects. All these patients were given treatment with Jianpi Shengxue Tablet for the first time. Results of blood routine examination, serum iron concentration, total iron binding capacity and ferritin were compared before and after treatment at different dates. Subjective symptoms and adverse reactions were also described. Jianpi Shengxue Tablet was given orally after meals, 3 tablets each time, 3 times a day. [Results] Hemoglobin level was(83.58±15.81) g/L(M±SD, n=200) before treatment, and(103.40±12.60) g/L(n=74) after 2 week's treatment, with a 24.3% increase(P=0.004 7). Hemoglobin concentration was(111.9±19.4) g/L(n=47) at the 4 th week after treatment, which was near normality;(126.0±9.49) g/L(n=30) at the 6~(th) week with complete normality and(130.7±7.95) g/L(n=23) at the 8~(th) week. MCV, MCH and MCHC increased gradually after treatment. Serum total iron biding capacity decreased, while serum iron and ferritin increased gradually, and the three indexes were significantly different at the 4~(th) week after treatment as compared with those before treatment(P≤0.01). Subjective symptoms were improved in the 1~(st) week from starting treatment among all the cases. The adverse events were mainly gastrointestinal irritation, occurring in 7/200 cases(3.5%). [Conclusions] Jianpi Shengxue Tablet is quite effective and safe in the treatment of iron deficiency anemia, with rapid comprehensive improvement of anemia-related symptoms and increase of hemoglobin and red blood cell parameters.
- Subjects
IRON deficiency anemia; ERYTHROCYTES; RETROSPECTIVE studies; FERRITIN; CHINESE medicine; BLOOD testing
- Publication
Medicinal Plant, 2021, Vol 12, Issue 5, p65
- ISSN
2152-3924
- Publication type
Article
- DOI
10.19600/j.cnki.issn2152-3924.2021.05.015