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- Title
A Leydig Cell Tumour in a Cat: Histological and Immunohistochemical Findings.
- Authors
Asproni, Pietro; Millanta, Francesca; Lorenzi, Davide; Poli, Alessandro
- Abstract
A 13-year-old intact male cat was submitted to castration after the finding of the enlargement of the right testis during the clinical visit. Macroscopically, a nodule of 2 cm of diameter was observed on the cut surface of the enlarged testis. Histologically, the nodule was composed by polyhedral to elongated cells with a large, eosinophilic, and vacuolated cytoplasm and small, round, and dark nuclei. These cells were arranged in acinar structures and solid sheets. The tumour was diagnosed as a Leydig cell tumour. Immunohistochemical analysis revealed that neoplastic cells were vimentin, calretinin, and melan-A positive, whereas a lack of immunoreactivity to cytokeratins confirmed the diagnosis. To our knowledge, this is the first description of a feline Leydig cells tumour without any concurrent testicular neoplasm or in a nonretained testis.
- Subjects
LEYDIG cell tumors; CANCER in animals; IMMUNOHISTOCHEMISTRY; CASTRATION; CAT diseases; EOSINOPHILS; TESTIS
- Publication
Case Reports in Veterinary Medicine, 2013, p1
- ISSN
2090-7001
- Publication type
Article
- DOI
10.1155/2013/670398