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- Title
High Transmission Rates of Early Omicron Subvariant BA.2 in Bangkok, Thailand.
- Authors
Petcharat, Sininat; Supataragul, Ananporn; Hirunpatrawong, Piyapha; Torvorapanit, Pattama; Klungthong, Chonticha; Chinnawirotpisan, Piyawan; Ninwattana, Sasiprapa; Thippamom, Nattakarn; Paitoonpong, Leilani; Suwanpimolkul, Gompol; Jantarabenjakul, Watsamon; Buathong, Rome; Joonlasak, Khajohn; Manasatienkij, Wudtichai; Rattanatumhi, Khwankamon; Chantasrisawad, Napaporn; Chumpa, Nuntana; Cotrone, Thomas S.; Fernandez, Stefan; Sriswasdi, Sira
- Abstract
The emergence of Omicron as the fifth variant of concern within the SARS-CoV-2 pandemic in late 2021, characterized by its rapid transmission and distinct spike gene mutations, underscored the pressing need for cost-effective and efficient methods to detect viral variants, especially given their evolving nature. This study sought to address this need by assessing the effectiveness of two SARS-CoV-2 variant classification platforms based on RT-PCR and mass spectrometry. The primary aim was to differentiate between Delta, Omicron BA.1, and Omicron BA.2 variants using 618 COVID-19-positive samples collected from Bangkok patients between November 2011 and March 2022. The analysis revealed that both BA.1 and BA.2 variants exhibited significantly higher transmission rates, up to 2-3 times, when compared to the Delta variant. This research presents a cost-efficient approach to virus surveillance, enabling a quantitative evaluation of variant-specific public health implications, crucial for informing and adapting public health strategies.
- Subjects
BANGKOK (Thailand); SARS-CoV-2 Omicron variant; SARS-CoV-2 Delta variant; SARS-CoV-2; COVID-19 pandemic; GENETIC mutation
- Publication
Advances in Virology, 2023, p1
- ISSN
1687-8639
- Publication type
Article
- DOI
10.1155/2023/4940767