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- Title
Cell-Phone-Based Platform for Biomedical Device Development and Education Applications.
- Authors
Smith, Zachary J.; Chu, Kaiqin; Espenson, Alyssa R.; Rahimzadeh, Mehdi; Gryshuk, Amy; Molinaro, Marco; Dwyre, Denis M.; Lane, Stephen; Matthews, Dennis; Wachsmann-Hogiu, Sebastian
- Abstract
In this paper we report the development of two attachments to a commercial cell phone that transform the phone's integrated lens and image sensor into a 350× microscope and visible-light spectrometer. The microscope is capable of transmission and polarized microscopy modes and is shown to have 1.5 micron resolution and a usable field-of-view of ∼150×150 ηm with no image processing, and approximately 350×350 ηm when post-processing is applied. The spectrometer has a 300 nm bandwidth with a limiting spectral resolution of close to 5 nm. We show applications of the devices to medically relevant problems. In the case of the microscope, we image both stained and unstained blood-smears showing the ability to acquire images of similar quality to commercial microscope platforms, thus allowing diagnosis of clinical pathologies. With the spectrometer we demonstrate acquisition of a white-light transmission spectrum through diffuse tissue as well as the acquisition of a fluorescence spectrum. We also envision the devices to have immediate relevance in the educational field.
- Subjects
MEDICAL sciences; CELL phones; IMAGE converters; MICROSCOPY; OPTICAL spectrometers; CLINICAL pathology
- Publication
PLoS ONE, 2011, Vol 6, Issue 3, p1
- ISSN
1932-6203
- Publication type
Article
- DOI
10.1371/journal.pone.0017150