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- Title
Mexican Arnica Anti-Inflammatory Action: Plant Age is Correlated with the Concentration of Anti—Inflammatory Sesquiterpenes in the Medicinal Plant Heterotheca inuloides Cass. (Asteraceae).
- Authors
Maldonado-López, Yuruxhi; Linares-Mazari, Edelmira; Bye, Robert; Guillermo Delgado, J.; Espinosa-García, J.
- Abstract
Mexican árnica (Heterotheca inuloides Cass.) is a widely used anti-inflammatory medicinal plant in Mexican folk medicine. Although it has been suggested that plant age, fertilization, and harvesting regime influence the concentration of secondary compounds affecting the therapeutic activity of the plant, the effect of these variables on the concentration of the Mexican árnica anti-inflammatory compounds was not known. We quantified anti-inflammatory sesquiterpenes (caryolan-1 9β-diol, cadalen-15-oic acid, 7-hydroxycadalene, 4-hydroxy-2-isopropyl-4, 7-dimethyl-1 [4H] naftalinone, 7-hydroxy-4αH-3, 4-dihydrocadalene, β-caryophyllene, and β-caryophyllene epoxide) in Mexican árnica plants subjected to fertilization and successive harvests of flowering stems, conditions that mimic the cultivation and harvesting for árnica in Mexico. Fertilization and successive harvesting and their interaction had no significant effect on the concentration of anti-inflammatory compounds. However, the concentrations of these compounds were 60% higher in flowering stems from 15-month-old plants than in those from 4- or 8-month-old plants and was independent of the number of harvests and fertilization regime applied.
- Subjects
MEXICO; ARNICA; HETEROTHECA; MEDICINAL plants; TRADITIONAL medicine; MEDICAL botany; ANTI-inflammatory agents; ANTI-inflammatory agents industry; HARVESTING
- Publication
Economic Botany, 2008, Vol 62, Issue 2, p161
- ISSN
0013-0001
- Publication type
Article