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- Title
Safety of platelet transfusion: past, present and future.
- Authors
Katus, M. C.; Szczepiorkowski, Z. M.; Dumont, L. J.; Dunbar, N. M.
- Abstract
Platelet components became routinely available to many institutions in the late 1960s and since then utilization has steadily increased. Platelets are produced by three principal methods and their manufacturing process is regulated by multiple agencies. As the field of platelet transfusion has evolved, a broad array of strategies to improve platelet safety has developed. This review will explore the evolution of modern platelet component therapy, highlight the various risks associated with platelet transfusion and describe risk reduction strategies that have been implemented to improve platelet transfusion safety. In closing, the reader will be briefly introduced to select investigational platelet and platelet-mimetic products that have the potential to enhance platelet transfusion safety in the near future.
- Subjects
BLOOD platelet transfusion; BLOOD transfusion; BLOOD collection; BUFFY coat; PLATELET-rich plasma
- Publication
Vox Sanguinis, 2014, Vol 107, Issue 2, p103
- ISSN
0042-9007
- Publication type
Article
- DOI
10.1111/vox.12146