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- Title
How to find TUFs.
- Authors
Rusk, Nicole
- Abstract
The article discusses a study on the use of high throughput sequencing of transcripts or RNA sequencing in analyzing transcripts with unknown function (TUFs). It says that Timothy Hughes' team of the University of Toronto compared TUFs through DNA microarray results and RNA sequencing and discovered false positive rates of transcripts. It discloses that extragenic transcripts might not be as ubiquitous as assumed, but plays an important function in biology and analyzing it is quite a challenge.
- Subjects
GENETIC code; NUCLEOTIDE sequence; DNA microarrays; GENETIC transcription; GENETIC regulation; HUGHES, Timothy
- Publication
Nature Methods, 2010, Vol 7, Issue 8, p582
- ISSN
1548-7091
- Publication type
Article
- DOI
10.1038/nmeth0810-582