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- Title
Vitamin D and depression: mechanisms, determination and application.
- Authors
Chunmei Geng; Shaikh, Abdul Sami; Wenxiu Han; Dan Chen; Yujin Guo; Pei Jiang; Geng, Chunmei; Han, Wenxiu; Chen, Dan; Guo, Yujin; Jiang, Pei
- Abstract
Depression is the most common debilitating psychiatric disease, the pathological mechanisms of which are associated with multiple aspects of neural function. While recent evidence has consistently suggested that a suboptimal vitamin D status is frequently observed in patients with depression, the results concerning whether vitamin D insufficiency is a causal factor of depression or is secondary to depressive behavior are conflicting; additionally, the lack of consistency of the method of vitamin D determination between labs has further worsened this confusion. Herein, we reviewed the neuroactivities of vitamin D that may be associated with depression and the current studies and clinical investigations to provide a full overview on the use of vitamin D in the treatment and prevention of depression.
- Subjects
CALCITRIOL; VITAMIN D; MENTAL illness
- Publication
Asia Pacific Journal of Clinical Nutrition, 2019, Vol 28, Issue 4, p689
- ISSN
0964-7058
- Publication type
journal article
- DOI
10.6133/apjcn.201912_28(4).0003