We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Photobiomodulation therapy for male infertility.
- Authors
Zupin, Luisa; Pascolo, Lorella; Luppi, Stefania; Ottaviani, Giulia; Crovella, Sergio; Ricci, Giuseppe
- Abstract
Male infertility is a worldwide critical condition that affects about the 7.5% of males in Europe leading to an increment of the couples referring to reproductive medicine units to achieve pregnancy. Moreover, in the recent years, an increased number of patients have required to freeze their gametes in order to preserve their fertility. Photobiomodulation (PBM) therapy is a potential treatment that has been used for different clinical application basically aimed at biostimulating cells and tissues. Here, we report a deep overview of the published studies, focusing on PBM mechanism of action, with the aim of expanding the knowledge in the field of laser light for a rational utilization of irradiation in the clinical practice. In the field of reproductive science, PBM was employed to increment spermatozoa's metabolism, motility, and viability, due to its beneficial action on mitochondria, leading to an activation of the mitochondrial respiratory chain and to the ATP production. This treatment can be particularly useful to avoid the use of chemicals in the spermatozoa culture medium as well as to promote the spermatozoa survival and movement especially after thawing or in largely immotile sperm samples.
- Subjects
MALE infertility treatment; REPRODUCTIVE health; SPERMATOZOA; MITOCHONDRIA; MALE infertility
- Publication
Lasers in Medical Science, 2020, Vol 35, Issue 8, p1671
- ISSN
0268-8921
- Publication type
Article
- DOI
10.1007/s10103-020-03042-x