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- Title
Androgenic hormones and the excess male mortality observed in COVID-19 patients: new convergent data.
- Authors
Lamy, Pierre-Jean; Rébillard, Xavier; Vacherot, Francis; de la Taille, Alexandre
- Abstract
During previous epidemics of coronaviruses, male sex was associated with worse clinical outcomes due to severe acute respiratory syndrome (SARS) in Hong Kong [[4]], and a higher risk of dying from Middle East respiratory syndrome (MERS) [[5]]. Keywords: SARS-CoV-2; TMPRSS2; Excess mortality; Androgens; Male EN SARS-CoV-2 TMPRSS2 Excess mortality Androgens Male 3121 3123 3 09/01/21 20210801 NES 210801 Dear Editor, According different studies and reports by live gender data tracker, more infected men than women seem to be dying from the new coronavirus, in different countries hit by the pandemic [[1]]. As specialists of prostate cancer, we were particularly interested to learn SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming.
- Subjects
COVID-19; ANDROGENS; SARS disease; MERS coronavirus; MIDDLE East respiratory syndrome
- Publication
World Journal of Urology, 2021, Vol 39, Issue 8, p3121
- ISSN
0724-4983
- Publication type
Letter
- DOI
10.1007/s00345-020-03284-y