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- Title
Gd-DOTA administration at MRI in children younger than 18 months of age: immediate adverse reactions.
- Authors
Emond S; Brunelle F; Emond, Sophie; Brunelle, Francis
- Abstract
<bold>Background: </bold>There is a paucity of evidence with regard to the safety of contrast medium administration at MRI in neonates and infants.<bold>Purpose: </bold>To assess immediate adverse reactions in children younger than 18 months of age during routine clinical utilization of gadoteric acid (Gd-DOTA) in a cohort of patients with nonselected indications.<bold>Materials and Methods: </bold>One hundred and four neonates and infants were enrolled in a postmarketing survey with Gd-DOTA (Dotarem, Guerbet, Roissy, France) from a single pediatric hospital. A standardized questionnaire was used to collect the patient information.<bold>Results: </bold>All included children, ages 3 days to 18 months, received one injection of Gd-DOTA (volume 0.6-4 ml). No immediate adverse event was reported.<bold>Conclusion: </bold>This postmarketing study involving neonates and infants suggests a favorable safety profile of Gd-DOTA in routine practice.
- Publication
Pediatric Radiology, 2011, Vol 41, Issue 11, p1401
- ISSN
0301-0449
- Publication type
journal article
- DOI
10.1007/s00247-011-2167-3