We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Trametes versicolor (Synn. Coriolus versicolor) Polysaccharides in Cancer Therapy: Targets and Efficacy.
- Authors
Habtemariam, Solomon
- Abstract
Coriolus versicolor (L.) Quél. is a higher fungi or mushroom which is now known by its accepted scientific name as Trametes versicolor (L.) Lloyd (family Polyporaceae). The polysaccharides, primarily two commercial products from China and Japan as PSP and PSK, respectively, have been claimed to serve as adjuvant therapy for cancer. In this paper, research advances in this field, including direct cytotoxicity in cancer cells and immunostimulatory effects, are scrutinised at three levels: in vitro, in vivo and clinical outcomes. The level of activity in the various cancers, key targets (both in cancer and immune cells) and pharmacological efficacies are discussed.
- Subjects
JAPAN; CHINA; TRAMETES versicolor; POLYSACCHARIDES; ADJUVANT treatment of cancer; CANCER treatment; POLYPORACEAE
- Publication
Biomedicines, 2020, Vol 8, Issue 5, p135
- ISSN
2227-9059
- Publication type
Article
- DOI
10.3390/biomedicines8050135