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- Title
Adenoviral hemorrhagic disease in a farmed elk (Cervus canadensis) in Alberta, Canada.
- Authors
Domshy, Katrice A.; Lung, Oliver; Nebroski, Michelle; Kruczkiewicz, Peter; Ayilara, Ifeoluwa; Woods, Leslie W.; Lowe, Evan; Davies, Jennifer L.
- Abstract
Adenoviral hemorrhagic disease (AHD), caused by deer atadenovirus A (OdAdV-1), affects captive and free-ranging cervids across North America. Here we present a case of AHD in a 6-month-old female elk calf from a farm in Alberta. Histopathology revealed multisystemic vasculitis with endothelial intranuclear inclusion bodies, pulmonary hemorrhage, and small intestinal hemorrhage characteristic of the acute systemic form of AHD. Immunohistochemistry was positive for OdAdV-1, confirming the diagnosis. Whole-genome sequencing of the virus was conducted for phylogenetic comparison. This is the 1st reported case of AHD in a farmed elk in Canada and the 1st reported case in an elk in Alberta. Key clinical message: Adenoviral hemorrhagic disease (AHD) is an emerging disease that should be investigated as a top differential when diagnosticians and veterinarians encounter young cervids found dead with pulmonary edema or hemorrhage and/or hemorrhagic enteropathy.
- Subjects
ALBERTA; ELK; HEMORRHAGIC diseases; CELLULAR inclusions; NUCLEOTIDE sequencing; PULMONARY edema
- Publication
Canadian Veterinary Journal / Revue Vétérinaire Canadienne, 2023, Vol 64, Issue 6, p524
- ISSN
0008-5286
- Publication type
Article