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- Title
ASSOCIATION OF HYPERURICEMIA WITH CRITICAL CORONARY ARTERY DISEASE.
- Authors
Khan, Gul Zaman; Zab, Jehan; Adnan, Fahar; Ahmed, Nisar; Akhtar, Ammar; Saleemi, Sohail
- Abstract
Objective: The study was conducted to determine the association of increased serum Uric acid level (SUA) with critical coronary artery disease (CAD) in patients subjected to coronary angiography. Methodology: 360 patients (180 cases with critical CAD and 180 controls without critical CAD) were enrolled in the study after taking informed consent. Demographic data like age, gender, diabetes mellitus, hypertension, family history of CAD, dyslipidemia, smoking and BMI was collected. Serum uric acid was advised and recorded in the questionnaire. Results: 360 patients with mean age 51.37 ± 6.5 years were included. 262 patients (72.8%) were male. 54 patients (20.8%) had hyperuricemia. 26.6% cases and 15.0% controls had hyperuricemia. Hyperuricemia was significantly associated with critical CAD (OR=2.06, CI 1.22-3.49, p=0.007). The association persisted after stratification according to age, gender, diabetes, hypertension, dyslipidemia, smoking, family history of IHD and BMI. Conclusion: There is a positive association between critical CAD and hyperuricemia.
- Subjects
CORONARY disease; HYPERURICEMIA; CORONARY angiography; URIC acid; INFORMED consent (Medical law)
- Publication
Pakistan Heart Journal, 2020, Vol 53, Issue 2, p147
- ISSN
0048-2706
- Publication type
Article
- DOI
10.47144/phj.v53i2.1813