We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Multiple developmental pathways lead to the generation of CD4 T-cell memory.
- Authors
Hojyo, Shintaro; Tumes, Damon; Murata, Akihiko; Tokoyoda, Koji
- Abstract
Long-term immunological memory mediated by CD4 T cells provides a rapid protection against previously encountered pathogens or antigens. However, it is still controversial how memory CD4 T cells are generated and maintained. Unclear definitions of T-cell memory may be partially responsible for this controversy. It is becoming clear that diverse pathways are responsible for the differentiation and long-term persistence of memory T cells. We herein discuss the diversity of memory cell generation, describing a novel population of resting memory CD4 T cells and their precursors.
- Subjects
LONG-term memory; T cells; T helper cells; IMMUNOLOGIC memory; MEMORY
- Publication
International Immunology, 2020, Vol 32, Issue 9, p589
- ISSN
0953-8178
- Publication type
Article
- DOI
10.1093/intimm/dxaa051