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- Title
Current State of the Art in the Adjuvant Systemic Treatment of Premenopausal Patients With Early Breast Cancer.
- Authors
Parisi, Francesca; Razeti, Maria Grazia; Blondeaux, Eva; Arecco, Luca; Perachino, Marta; Tagliamento, Marco; Levaggi, Alessia; Fregatti, Piero; Poggio, Francesca; Lambertini, Matteo
- Abstract
Breast cancer is the most frequent malignancy diagnosed in premenopausal women. In this age group, breast tumors tend to be diagnosed at more advanced stages and to harbor more aggressive biological features. In addition, specific age-related issues including genetic counseling, fertility preservation, impact on social and couple relationships, working life, and management of long-term side effects should be considered highly relevant when managing early breast cancer in premenopausal women. Therefore, the care of these patients is particularly complex and a multidisciplinary approach is mandatory. The present review summarizes the current state of art in the adjuvant systemic treatment of premenopausal women with early breast cancer focusing on the optimal chemotherapy, endocrine therapy, and targeted therapy approaches in this specific patient population.
- Subjects
ANTINEOPLASTIC agents; BREAST cancer prognosis; BREAST tumor diagnosis; THERAPEUTIC use of monoclonal antibodies; AGE; BREAST tumors; CANCER patient medical care; COMBINED modality therapy; GENETIC counseling; HEALTH care teams; HORMONES; INTERPERSONAL relations; MEDICAL care; CANCER; THERAPEUTICS; PERIMENOPAUSE; EARLY detection of cancer
- Publication
Clinical Medicine Insights: Oncology, 2020, Vol 14, p1
- ISSN
1179-5549
- Publication type
Article
- DOI
10.1177/1179554920931816