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- Title
Antibacterial spectrum assessments of Solanum nigrum L. fruit juice.
- Authors
Kusuma, Sri Agung Fitri; Wardati, Yulia; Anggraeni, Wulan
- Abstract
Aim: The objective of this study was to assess the antibacterial spectrum activity of fruit juice of Solanum nigrum found in Indonesia. Materials and Methods: The Solanum fruits were juiced using a sterile blender followed by the pulp separation to obtain the Solanum juice. The juice then analyzed for phytochemical content using standard methods and evaluated for its antibacterial spectrum against Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922. The antibacterial activities were done using the agar well diffusion method. In addition to this, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) determinations were conducted by macrodilution assay. Results and Discussion: Phytochemical analysis revealed that the fruit juice of S. nigrum possessed flavonoids, tannins, alkaloids, and saponins. Solanum fruit juice presented a broad spectrum of antibacterial due to its inhibition against both bacteria. However, the juice worked more effectively against E. coli compared to S. aureus. These data scientifically proved by the resulted values of MIC and MBC determination, revealed that the juice had the much less MIC and MBC values against E. coli than S. aureus, ranging from 30% to 45% v/v and 45% to 60% v/v, respectively. Conclusion: The current study assured the broad spectrum of antibacterial activity of S. nigrum fruit juices.
- Publication
Drug Invention Today, 2019, Vol 12, Issue 11, p2702
- ISSN
0975-7619
- Publication type
Article