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- Title
Antihemolytic activity of Solanum virginianum.
- Authors
Madhumithaa, S.; Vishnupriya, V.; Gayathri, R.; Selvaraj, J.
- Abstract
Aim: The aim of the study was to find the antihemolytic activity of Solanum virginianum. Background: Medicinal plant S. virginianum L is belong to the family Solanaceae, commonly known as yellow berried nightshade. Recent scientific studies have emphasized the possible use of S. virginianum in modern medicine. Hemolysis is the rupturing (lysis) of red blood cells (erythrocytes) and the release of their contents (cytoplasm) into surrounding fluid (e.g., blood plasma). The antihemolytic activity of the plant extract is determined using the antihemolysis formula and spectrophotometric method. Materials and Methods: The study deals with the antihemolysis potential of S. virginianum ethanol is extract. An erythrocytes suspension is created from a “A†positive patient and a hemolytic activity is performed by an in vitro procedure. Antihemolytic potential of the extract was inspected by spectrophotometric procedure checked by addition of the plant and compared with the standard. The level of percentage hemolysis by the extracts was calculated according to the following formula: % of hemolysis = At-An/Ac-Anx100. Results: The results of this study conclude that the ethanol extracts from the plant of S. virginianum are non/less toxic to the human erythrocytes. Conclusion: The test tube with the strongest concentration of the plant extract had a hemolytic action whereas the test tube with the weakest plant extract had an antihemolytic action. Through the experiment, the hemolytic activity of the S. virginianum plant extract significantly increased in a dose-dependent manner.
- Subjects
ERYTHROCYTES; SOLANUM; SOLANACEAE; PLANT extracts; BLOOD plasma; MEDICINAL plants
- Publication
Drug Invention Today, 2019, Vol 11, Issue 7, p1549
- ISSN
0975-7619
- Publication type
Article