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- Title
Free radical scavenging potentials of Triphala: A medicinal herb used in Indian Ayurvedic system of medicine.
- Authors
Rekha, U. Vidhya; Anita, M.; Bhuvaneswarri, J.; Jayamathi, G.; Sadhana, K.; Ramya, V.; Paddmanabhan, Preethe; Selvaraj, J.
- Abstract
Background: Triphala is a commonly used Indian Ayurvedic formula made of the dried powder of three different fruits: Hence, its name: Tri (Three) and phala (Fruit). Amla (Emblica officinalis), Haritaki (Terminalia chebula), and Bibhitaki (Terminalia bellirica) are mixed in equal parts to make a proper Triphala. Aim: The study was designed to assess the effects of Triphala churna on the free radical scavenging activities such as hydrogen peroxide, nitric oxide (NO) radical, and superoxide anion radical scavenging activities in vitro. Results: The Triphala churna showed potent free radical scavenging activity in concentration-dependent manner. It exhibited potent H2O2 scavenging property, and the IC50 was found to be 0.06 Mcg/ml, and for the standard drug, Vitamin C was 0.06 Mcg/ml. NO scavenging property of Triphala was found to be 0.06 Mcg/ml and for Vitamin C 0.09 Mcg/ml and superoxide anion of Vitamin C was found to be 0.053 Mcg/ml and 0.053 Mcg/ml, respectively. Conclusion: The study concluded that Triphala as a whole is to be expected to be more effective due to the combined activity of the individual components. Hence, it is concluded that Triphala may provide effective complementary or alternative treatment regimens for patients with suffering from health ailments.
- Subjects
FREE radicals; AYURVEDIC medicine; HERBAL medicine; VITAMIN C; TERMINALIA chebula; SUPEROXIDES
- Publication
Drug Invention Today, 2019, Vol 12, Issue 3, p407
- ISSN
0975-7619
- Publication type
Article