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- Title
Flow-mediated vasodilation and endothelial function in Mexican patients with type 2 diabetes mellitus, a cross-sectional study in western Mexico.
- Authors
Balleza Alejandri, Luis Ricardo; Grover Páez, Fernando; González Campos, Erick; Becerra Ramos, Carlos Gerardo; Cardona Gutierrez, German; Pascoe Gonzalez, Sara; Galan Ruiz, Claudia Yanette; Esparza Pimentel, Javier; Cardona Müller, David
- Abstract
Flow-mediated vasodilation and endothelial function in Mexican patients with type 2 diabetes mellitus, a cross-sectional study in western Mexico. Introduction: Mexico is a country with high mortality due to diabetes complications (1); constant hyperglycemia in patients with diabetes leads to endothelial damage, which is the main risk factor for the development of macro and microvascular complications, leading to an increased risk of mortality (2). Flow-mediated vasodilation (FMD) is one of the most widely used techniques for the evaluation of endothelial function and can be used as predictor of cardiovascular risk (3,4). Objective: The objective of this study is to determine the FMD values and hemodynamic characteristics in Mexican patients with type 2 diabetes mellitus in western Mexico. Methods: FMD were measured with a high-resolution semi-automatic ultrasound UNEX-EF 38G (UNEX Co. Ltd Nagoya Japan). Measurement of arterial tension were made with an OMRON electronic digital sphygmomanometer (HEM 907 XL). Results: 65 patients, (28 men and 37 women) with a mean age of 52.46 ± 11.71, we found a difference between the basal and final diameters and blood flow between men and women (4.67 ± 0.76 vs 3.42 ± 0.69 p 0.001; 4.96 ± 0.76 vs 3.66 ± 0.70 p 0.001; (10.5 ± 8.05 vs 4.59 ± 3.56 p 0.020); an inverse correlation was found between FMD and SBP (r = - 0.265 p 0.33). Conclusion: We found a lower FMD in women than in men, it is also noteworthy the differences found in the flow and bIMT between the individuals in the study, the above can be explained by the inherent hormonal effects of each sex.
- Subjects
VASODILATION; ENDOTHELIAL cells; CARDIOVASCULAR diseases
- Publication
Artery Research, 2023, Vol 29, Issue 1, pS25
- ISSN
1872-9312
- Publication type
Article
- DOI
10.1007/s44200-022-00028-8