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- Title
Antitumor and Immunostimulating Activities of the Extracts from Tremella aurantialba Fruting Bodies in vitro.
- Authors
DU Xiu-ju; ZHANG Jing-song; JIA Wei
- Abstract
In order to screen biological activity extracts from Tremella aurantialba, the systematic solvent extraction was used to extract the fruiting bodies. Firsdy, the fruiting bodies powder of T. aurantialba were extracted by chloroform (Chl), ethyl acetate (EA), ethanol (Eth), respectively, then three extracts with different polarity were prepared. Secondly, the air-dried residua after ethanol were extracted by water at 80 °C , water at 100 °C, 3% ammonium oxalate and 5% sodium hydroxide, respectively, and accordingly four extracts TAFW1, TAFWr, TAFWn and TAFWj were prepared. Furthermore, the inhibition effects of extracts in organic protion on cells L1210 and SW620 were determined. The results showed that the inhibition effects of Chl-portion on cells L1210 and SW620 was the best among the three extracts. The immunostimulating activity assay of four extracts showed that TAFWr had almost the same proliferation rate as that of TAFW1 and they showed a bit lower immunostimulating activity compared with the TAFWj (P < 0.05 ).
- Subjects
ANTINEOPLASTIC agents; IMMUNOLOGICAL adjuvants; TREMELLA; PLANT extracts; SOLVENT extraction; CHLOROFORM; POLYSACCHARIDES
- Publication
Natural Product Research & Development, 2011, Vol 23, Issue 2, p351
- ISSN
1001-6880
- Publication type
Article