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- Title
Clinical presentation and CT/MRI findings of alveolar soft part sarcoma: a retrospective single-center analysis of 14 cases.
- Authors
Tian, Li; Cui, Chun-Yan; Lu, Su-Ying; Cai, Pei-Qiang; Xi, Shao-Yan; Fan, Wei
- Abstract
<bold>Background: </bold>Alveolar soft part sarcoma (ASPS) is a relatively rare malignant tumor and early diagnosis and appropriate treatment for ASPS are essential for a good prognosis.<bold>Purpose: </bold>To retrospectively review the clinical presentation and computed tomography (CT) and magnetic resonance imaging (MRI) findings of ASPS so as to improve the accuracy of imaging diagnosis.<bold>Material and Methods: </bold>Fourteen patients with pathologically proven ASPS were enrolled. Their clinical and imaging findings were retrospectively reviewed.<bold>Results: </bold>The median age of the patients was 29 years (range, 13-37 years). Most tumors were located in the soft tissues of the trunk and lower limbs. The median maximal diameter of the masses was 91 mm. Thirteen masses presented with ovoid or irregular shapes. Eleven masses had less clear boundaries. Compared with the adjacent muscles, the masses were isodense or hypodense on CT, hypo-, iso-, or hyperintense on T1-weighted images, and heterogeneous hyperintense on T2-weighted images. Intense enhancement was seen after contrast agent administration, with prominent intra- or peri-tumoral feeders on CT or flow voids on MRI. By the end of the last follow-up, 13 patients had distant metastasis and three patients had local recurrence.<bold>Conclusion: </bold>ASPS should be included in the differential diagnosis when a bulky, heterogeneous soft tissue mass in the trunk and the lower limbs with intense enhancement after contrast administration and prominent intra- or peri-tumoral feeders on CT or flow voids on MRI is seen, particularly in young patients.
- Subjects
ALVEOLAR soft part sarcomas; SARCOMA; COMPUTED tomography; MAGNETIC resonance imaging; EARLY diagnosis; AGE factors in disease; DIAGNOSIS
- Publication
Acta Radiologica, 2016, Vol 57, Issue 4, p475
- ISSN
0284-1851
- Publication type
journal article
- DOI
10.1177/0284185115597720