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- Title
Aldosterone, Renin, and Diabetes Mellitus in African Americans: The Jackson Heart Study.
- Authors
Joseph, Joshua J; Echouffo-Tcheugui, Justin B; Kalyani, Rita R; Yeh, Hsin-Chieh; Bertoni, Alain G; Effoe, Valery S; Casanova, Ramon; Sims, Mario; Correa, Adolfo; Wu, Wen-Chih; Wand, Gary S; Golden, Sherita H
- Abstract
We examined the association of both aldosterone and renin, with insulin resistance, β-cell function, and incident diabetes in a large African American cohort. Renin-angiotensin-aldosterone system with higher levels of aldosterone and renin is associated with insulin resistance, compensatory increased β-cell function and incident diabetes in African Americans.
- Subjects
ISLANDS of Langerhans; RENIN-angiotensin system; ALDOSTERONE; BLACK people; BLOOD pressure; GLYCOSYLATED hemoglobin; INSULIN resistance; TYPE 2 diabetes; RENIN; RESEARCH funding; BODY mass index; PHYSIOLOGY
- Publication
Journal of Clinical Endocrinology & Metabolism, 2016, Vol 101, Issue 4, p1770
- ISSN
0021-972X
- Publication type
journal article
- DOI
10.1210/jc.2016-1002