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- Title
Phylogenetic Analysis of Clinically Relevant Fusarium Species in Iran.
- Authors
Najafzadeh, Mohammad Javad; Dolatabadi, Somayeh; de Hoog, Sybren; Esfahani, Mahmoud Karimizadeh; Haghani, Iman; Aghili, Seyed Reza; Ghazvini, Roshanak Daei; Rezaei-Matehkolaei, Ali; Abastabar, Mahdi; Al-Hatmi, Abdullah M. S.
- Abstract
Fungi of the genus Fusarium are well known as major plant pathogens but also cause a broad spectrum of human infections. Sixty-three clinical isolates, collected during 2014–2017, were identified using a part of the TEF1 gene as barcoding marker. Fusarium fujikuroi species complex (FFSC, n = 41, 65%) showed to be the dominant etiological agent, followed by F. solani species complex (FSSC, n = 14, 22%) and F. oxysporum species complex (FOSC, n = 7, 11%). There was one strain belonging to F. lateritium species complex (FLSC, n = 1, 1.5%). For final identification, a phylogenetic tree was constructed including the type strains of each species complex. Most cases of fusariosis were due to nail infection (n = 38, 60.3%), followed by keratitis (n = 22, 34%). Fusarium infections are difficult to be treated due to their intrinsic resistance to different azoles; however, accurate and fast identification of etiological agents may enhance management of the infection. We present the first phylogenetic study on clinical Fusarium spp. from Iran.
- Subjects
IRAN; FUSARIOSIS; FUSARIUM; SPECIES; PHYTOPATHOGENIC microorganisms; RHIZOCTONIA solani; AZOLES
- Publication
Mycopathologia, 2020, Vol 185, Issue 3, p515
- ISSN
0301-486X
- Publication type
Article
- DOI
10.1007/s11046-020-00460-x