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- Title
Three-dimensional maximum principal strain using cardiac computed tomography for identification of myocardial infarction.
- Authors
Tanabe, Yuki; Kido, Teruhito; Kurata, Akira; Sawada, Shun; Suekuni, Hiroshi; Kido, Tomoyuki; Yokoi, Takahiro; Uetani, Teruyoshi; Inoue, Katsuji; Miyagawa, Masao; Mochizuki, Teruhito
- Abstract
<bold>Objectives: </bold>To evaluate the feasibility of three-dimensional (3D) maximum principal strain (MP-strain) derived from cardiac computed tomography (CT) for detecting myocardial infarction (MI).<bold>Methods: </bold>Forty-three patients who underwent cardiac CT and magnetic resonance imaging (MRI) were retrospectively selected. Using the voxel tracking of motion coherence algorithm, the peak CT MP-strain was measured using the 16-segment model. With the trans-mural extent of late gadolinium enhancement (LGE) and the distance from MI, all segments were classified into four groups (infarcted, border, adjacent, and remote segments); infarcted and border segments were defined as MI with LGE positive. Diagnostic performance of MP-strain for detecting MI was compared with per cent systolic wall thickening (%SWT) assessed by MRI using receiver-operating characteristic curve analysis at a segment level.<bold>Results: </bold>Of 672 segments excluding16 segments influenced by artefacts, 193 were diagnosed as MI. Sensitivity and specificity of peak MP-strain to identify MI were 81 % [95 % confidence interval (95 % CI): 74-88 %] and 86 % (81-92 %) compared with %SWT: 76 % (60-95 %) and 68 % (48-84 %), respectively. The area under the curve of peak MP-strain was superior to %SWT [0.90 (0.87-0.93) vs. 0.80 (0.76-0.83), p < 0.05].<bold>Conclusions: </bold>CT MP-strain has a potential to provide incremental value to coronary CT angiography for detecting MI.<bold>Key Points: </bold>• CT MP-strain allows for three-dimensional assessment of regional cardiac function. • CT-MP strain has high diagnostic accuracy for detecting myocardial infarction. • CT-MP strain may assist in tissue characterisation of myocardium assessed by LGE-MRI. • CT-MP strain provides incremental values to coronary CTA for detecting myocardial infarction.
- Subjects
COMPUTED tomography; MEDICAL imaging systems; THREE-dimensional imaging; MYOCARDIAL infarction diagnosis; CARDIAC arrest; MAGNETIC resonance imaging; PERFORMANCE of imaging systems; DIAGNOSIS; COMPARATIVE studies; DIAGNOSTIC imaging; CARDIAC contraction; RESEARCH methodology; MEDICAL cooperation; MYOCARDIAL infarction; RESEARCH; PILOT projects; EVALUATION research; PREDICTIVE tests; CONTRAST media; RETROSPECTIVE studies; RECEIVER operating characteristic curves; CORONARY angiography
- Publication
European Radiology, 2017, Vol 27, Issue 4, p1667
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-016-4550-9