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- Title
Liraglutide-Induced Hemorrhagic Pancreatitis in a Nondiabetic Patient.
- Authors
Dolan, Russell D.; Bazarbashi, Ahmad Najdat; Lo, Amy; Smith, Benjamin N.
- Abstract
Liraglutide is a glucagon-like peptide 1 (GLP-1) analog with a primary effect of increased glucose-dependent insulin secretion and decreased gastric emptying. It serves as a feasible medical weight loss option because of the drug's effect of invoking satiety and lowering caloric intake. Despite emerging efficacy, the GLP-1 class has been associated with severe, although rare, adverse events, including pancreatitis. Previous investigations demonstrated the greatest association between GLP-1 agonist-associated pancreatitis in diabetic populations; however, liraglutide dosing is higher in weight loss formulations, placing the weight loss population at higher risk. We present a case of liraglutide-induced acute pancreatitis in a patient without diabetes.
- Subjects
OBESITY complications; HEALTH promotion; HEMORRHAGE; OBESITY; BARIATRIC surgery; PANCREATITIS; RISK assessment; WEIGHT loss; GLUCAGON-like peptide-1 agonists
- Publication
ACG Case Reports Journal, 2020, Vol 7, Issue 5, p1
- ISSN
2326-3253
- Publication type
Article
- DOI
10.14309/crj.0000000000000380