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- Title
Concept of onychodermis has no microanatomical basis.
- Authors
Perrin, Christophe; Coutts, Michael
- Abstract
The article challenges the concept of onychodermis, which is described as an area beneath the nail matrix and nail bed. The authors argue that the concept is confusing and lacks microanatomical basis. They question the claim made by Dr. Lee and colleagues that onychomatricoma is a tumor of onychofibroblasts within the onychodermis. The authors suggest that onychomatricoma is actually a CD34-positive matrix tumor and not an onychofibroblastic tumor. They also discuss their own study on onychomatricoma, which found a link to RB1 loss and suggests the potential diagnostic value of Lef-1.
- Subjects
NAILS (Anatomy)
- Publication
Histopathology, 2024, Vol 84, Issue 4, p707
- ISSN
0309-0167
- Publication type
Article
- DOI
10.1111/his.15089