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- Title
Evaluation of the correlation between interleukin 1ß levels in peri-implant crevicular fluid as an adjunctive diagnostic marker with clinical and radiographic parameters for assessing the peri-implant health status.
- Authors
KHATRI, MANISH; BANSA, MANSI; PURI, KOMAL; MEHROTRA, SOURABH; KUMAR, ASHISH; REHAN, MOHD
- Abstract
Background: Interleukin-1ß (IL-1ß) is one of the most important cytokines that seems to have an important role in the inflammatory process in gingival and peri-implant tissues. As peri-implant crevicular fluid (PICF) provides with a more swift and objective measure of the disease activity, the present study was conducted to evaluate IL-1ß level in PICF as a biochemical marker and to investigate its correlation with clinical parameters and radiological parameters. Materials and Methods: After evaluating all the patients following inclusion and exclusion criteria, 60 patients were selected for the study. After 3-4 months of implants placement, the implants were exposed following standard surgical procedure. PICF sample from implant site was taken 3 days after suture removal with gingival former still in place followed by measurement of clinical and radiological parameters. Results: There was significant increase in IL-1ß levels in both the follow-ups from baseline with variable and minimal change in the clinical parameters and radiological parameters as well, which shows that IL-1ß levels change significantly even when there is a minimal gingival inflammation. Conclusion: Therefore, IL-1ß level in PICF can be used as an adjunctive diagnostic marker to clinical and radiographic parameters for assessing the peri-implant health status.
- Subjects
GINGIVAL fluid; BIOMARKERS; GINGIVA; OPERATIVE surgery; INFLAMMATION
- Publication
National Journal of Maxillofacial Surgery, 2022, Vol 13, Issue 3, p421
- ISSN
0975-5950
- Publication type
Article
- DOI
10.4103/njms.njms_337_21